
Biomedical Scientist & Educational Advisor
Most patients don’t struggle with knowing what to do. They struggle with changing what they do. Clinicians see this daily—patients understand the basics of “eat better, move more, sleep enough,” yet lasting success remains elusive. The challenge is not a lack of information; it’s a lack of personalization and prioritization.
The ExtendingME Customized Diet Panel helps bridge that gap. By analyzing single nucleotide polymorphisms (SNPs) tied to carbohydrate, protein, and fat metabolism, the panel identifies where diet and lifestyle changes will make the greatest impact. Instead of giving patients broad, overwhelming goals, clinicians can prescribe focused, genetics-informed changes that are realistic, measurable, and sustainable.
From Knowledge to Change
Generic diets and lifestyle programs often fail because they ignore individual biology. A low-carb plan may work brilliantly for one patient and leave another exhausted. High-protein diets build lean mass in some but worsen glucose stability in others. Restrictive fat guidelines help certain individuals yet elevate cholesterol in others.
The Customized Diet Panel takes the guesswork out of this variability. By highlighting which macronutrients each patient is most sensitive to, it directs clinicians to the specific changes most likely to produce meaningful results. This makes nutrition counseling not only more precise, but also more achievable—patients can focus on changes that matter, not endless trial-and-error.
Practical Dietary Changes Guided by Genetics
Carbohydrate handling (FGF21, TCF7L2, MTNR1B):
Instead of blanket “low-carb” prescriptions, clinicians can recommend targeted changes such as replacing refined carbs with low-glycemic options, reducing late-night carbohydrate intake, or emphasizing post-meal activity. Patients make fewer but more effective dietary shifts, supported by their genetics.
Protein response (GCKR, PPP1R3B):
Some patients benefit from higher protein intake, while others experience glucose elevations with excessive protein. The key change may be in distribution—moderate protein across three meals combined with resistance training—to preserve lean mass without destabilizing blood sugar.
Fat metabolism (APOA2, PPARG, FADS):
Rather than broad “low-fat” advice, clinicians can guide patients toward improving quality over quantity: reducing saturated fat, emphasizing monounsaturated fat (MUFA) or polyunsaturated fat (PUFA) depending on genetic response, and pairing dietary changes with cardiovascular lifestyle measures.
Lifestyle Changes That Amplify Nutrition
Genetics may direct diet, but lifestyle changes ensure it works in practice. The panel allows clinicians to connect dietary recommendations with complementary behaviors:
- Sleep changes: Patients with MTNR1B variants tied to impaired glucose control benefit from consistent sleep routines and earlier meal timing.
- Activity changes: For carbohydrate-sensitive patients, simple post-meal walks improve glycemic response.
- Stress changes: For patients carrying inflammatory SNPs (e.g., IL6, APOA2), combining anti-inflammatory dietary fats with mindfulness or yoga reduces metabolic burden.
These lifestyle modifications are often incremental, yet when aligned with diet and genetics, they transform outcomes.
Sustainable Health Through Incremental Change
Optimum health is not achieved through radical overhauls. Most patients fail when asked to change everything at once. Genetics helps clinicians narrow the focus to two or three changes that will matter most.
For example:
- A patient genetically prone to carbohydrate overconsumption (FGF21) may be asked to prioritize low-glycemic swaps and add a post-dinner walk—two clear, realistic changes.
- A patient with poor MUFA metabolism may shift cooking oils and focus on stress reduction—again, achievable changes with measurable benefit.
The Customized Diet Panel equips clinicians to move from “here’s a diet” to “here are the specific changes that fit your biology and your lifestyle.” This makes adherence easier and progress more consistent.
The Bigger Picture: Precision Living
At its core, the panel is more than a nutrition tool—it’s a change tool. It empowers clinicians to:
- Identify the most impactful diet modifications
- Pair those with lifestyle shifts that reinforce outcomes
- Support energy, mood, and resilience in everyday life
- Help patients adopt sustainable prevention strategies
Optimum health isn’t built from sweeping instructions; it’s achieved through precise, incremental changes that patients can maintain over time. The Customized Diet Panel gives clinicians the roadmap to make this possible.
Clinical Takeaways
Genetics pinpoints change: SNP insights reveal which macronutrient shifts matter most for each patient.
Diet changes are specific: Carbohydrate timing, protein distribution, and fat quality outperform generic restrictions.
Lifestyle changes amplify diet: Sleep, activity, and stress management align with nutrition for better outcomes.
Incremental change is sustainable: The panel helps clinicians prescribe 2–3 high-impact changes instead of overwhelming patients.
Optimum health is achieved through balance: Integrating diet and lifestyle changes creates long-term adherence and resilience.
“The power of genetics is not in more knowledge—it’s in guiding real, sustainable changes patients can make.”
The ExtendingME Customized Diet Panel analyzes SNPs using RealTime PCR with the Illumina Global Screening Array. All testing is performed in a CLIA-certified laboratory, and results are interpreted against peer-reviewed literature linking genetic variants to macronutrient metabolism, glucose regulation, lipid handling, and lifestyle-related health outcomes.
Bring precision change into your practice.
Use the ExtendingME Customized Diet Panel to identify the specific dietary and lifestyle changes that align with each patient’s genetics—making prevention and wellness not just possible, but sustainable.