Epigenetics Panel & Report
Understanding
Epigenetics
Epigenetics is the science of how gene activity is regulated without altering the DNA sequence. It focuses on methylation patterns, molecular “switches” that turn genes on or off—affecting cellular function, inflammation control, immune balance, cognitive performance, and vision health.
By studying these methylation markers, healthcare professionals gain deeper insight into biological aging trajectories, enabling personalized interventions to support longevity, disease prevention, and improved patient outcomes.
Overview

- The Epigenetics Panel by ExtendingMe analyzes key CpG methylation markers across vision, immune, and brain-related pathways to uncover hidden patterns of biological aging. It empowers healthcare professionals to detect early risks, personalize care strategies, and enhance overall patient health outcomes.
- Our Epigenetics Panel generates a Methylation Score - a composite metric that reflects biological function and gene regulation in the present moment.
What This Test Covers
The panel evaluates three core areas critical to healthy aging
Vision Aging
Assesses methylation markers impacting retinal resilience, mitochondrial function, oxidative defense, and susceptibility to age-related macular degeneration.
Immune Aging
Examines methylation-driven changes affecting inflammation control, oxidative balance, immune cell stability, and overall immune resilience.
Brain and Cognition
Analyzes markers linked to synaptic function, cognitive performance, and neuroprotection, enabling early detection of cognitive decline risks.
Why It Matters
- Assesses the current biological state of gene expression, not just inherited risk
- Detects early signs of dysfunction in vision, brain, and immune systems before symptoms appear
- Methylation insights guide targeted nutrition, supplementation, labs to consider and lifestyle strategies
- Methylation scores serve as an aging biomarker, tracking measurable progress or decline over time
Who Should Take This Test
This panel is ideal for healthcare providers specializing in
Preventive & functional medicine
Longevity & anti-aging programs
Neurodegenerative risk assessment
Integrative care focused on precision health
What You’ll Receive

Comprehensive Epigenetic Report
• Methylation Scores for each domain: vision, immune, and brain
• Biological vs. Chronological Age comparison per domain
• Epigenomic Status Snapshot showing gene-level methylation classification

Personalized Insights
Gene-level insights with names and functional summaries of key genes linked to biological aging.
Personalized recommendations for lifestyle, nutrition, and supplement strategies.

Provider Portal Access
Secure digital access to the ExtendingME Provider Portal for test ordering and result tracking.

Turnaround Time
Results will be available approximately 4 weeks from the receipt of the sample and will be securely delivered through the Provider Portal, enabling seamless access, viewing, and sharing of reports.
Collection Method
ExtendingME kits include all necessary self-collection devices for non-invasive, at-home saliva collection, making it easy to deliver real-time, data-driven healthcare solutions without the need for lab visits.
Start Measuring What Truly Matters
Discover how your patients are aging at the molecular level. Order the Epigenetics Panel today and bring precision-driven, personalized care to the forefront of your practice.
