Longevity Panel Part Two & Report
Overview
- The ExtendingME Longevity Panel Part Two is based on the Hallmarks of Aging, focusing on advanced and regulatory biological processes that govern the pace of aging and cellular renewal. This panel analyzes key genetic and epigenetic pathways that influence biological age acceleration, regeneration capacity, and metabolic signaling, enabling precision-guided longevity optimization.
- Longevity Panel Part Two focuses on downstream and integrative hallmarks of aging, including epigenetic alterations, cellular senescence, autophagy efficiency, proteostasis, and cellular stress response, and nutrient-sensing dysregulation the mechanisms that control how fast aging progresses and how effectively the body repairs itself.
- By uncovering how rapidly biological aging is unfolding and identifying modifiable molecular levers, Part Two empowers healthcare professionals to move beyond risk detection toward active longevity modulation. Clinicians can use these insights to personalize nutrition, supplementation, lifestyle, and regenerative strategies to slow biological aging, support cellular resilience, and optimize long-term vitality and function.
What This Test Covers
The Longevity Panel Part Two is divided into core health categories, each offering detailed insights into specific traits and functions
Cellular Renewal &
Autophagy Function
Evaluates the body’s ability to clear damaged cells, maintain tissue integrity, and regulate repair mechanisms essential for healthy aging
- Biological Aging Resilience
- BAG4-Linked Apoptotic Stress Regulation
Epigenetic Aging & Regenerative Capacity
Assesses biological age acceleration, regenerative potential, and genetic factors influencing cell-to-cell communication, stem cell function, and epigenetic regulation
- Epigenetic Aging Susceptibility
Protein Folding &
Cellular Stress Response
Examines genetic capacity to maintain protein quality control, prevent misfolding, and protect against neurodegenerative processes
- ER Stress Response Dysregulation
Metabolic Aging & Nutrient Sensing
Evaluates nutrient sensing, metabolic efficiency, and micronutrient regulation for long-term health and disease prevention
- Insulin Secretion Regulatory Profile
- Calcium Regulation Efficiency
- CoQ10 Biosynthesis & Utilization Efficiency
- Vitamin D Binding & Transport Variants
- Magnesium Absorption & Retention Risk
- VLSFA Metabolic Pathway Imbalance
Why It Matters
This panel reveals the hidden biological factors that determine how patients age, turning complex genetic data into clear, actionable strategies for longer, healthier lives. It allows healthcare professionals to
- Pinpoint hidden risks in cellular repair, epigenetic aging, metabolism, and inflammation
- Design targeted, measurable interventions that improve outcomes and extend healthspan
- Strengthen patient trust and retention through cutting-edge, preventive solutions
- Differentiate their practice as a leader in advanced longevity medicine
Who Should Take This Test
For healthcare professionals managing patients who need more than standard aging assessments.
The Longevity Advanced Panel is ideal for
Complex cases needing multi-system genetic analysis.
High-risk patients with strong family history of chronic disease.
Early biological decline despite “normal” labs.
Midlife and older adults aiming to preserve vitality and independence.
Precision and performance medicine patients, executives, elite athletes, and high-demand professionals who require peak function over decades.
What You’ll Receive
Comprehensive Genetic Report
Organized into clear categories and subcategories, covering key health areas.
Personalized Insights
Actionable insights for nutrition, lifestyle, labs to consider and supplementation based on patients' unique genetic profile.
Provider Portal Access
Secure digital access via the ExtendingME Provider Portal for seamless report viewing, sharing.
SNP-Specific Risk Interpretations (optional, based on your requirements)
For providers seeking deeper genetic insights, we offer detailed SNP-level interpretations.
- Genetic marker identification (e.g., gene name, rsID)
- Patient genotype results and what it means for your patient's health
- Scientific explanation of how these genes influence specific health traits
Turnaround Time
Results will be available approximately 2 weeks from the receipt of the sample and will be securely delivered through the Provider Portal, enabling seamless access, viewing, and sharing of reports.
Collection Method
ExtendingME kits include all necessary self-collection devices for non-invasive, at-home saliva collection, making it easy to deliver real-time, data-driven healthcare solutions without the need for lab visits.
Harness the power of 50+ SNPs across multiple hallmarks of aging for deep, multi-system insight. Connect the dots between cellular renewal, metabolism, inflammation, and nutrient balance to create truly next-generation longevity plans.
