Detoxification Panel & Report
Overview
- The Detoxification Panel provides a deeper look into the genetic pathways that influence how the body processes oxidative stress, hormones, medications, environmental compounds, and metabolic by-products.
- Analysing 55+ SNPs across key detoxification and metabolic pathways, the panel helps healthcare professionals identify genetic tendencies that may influence antioxidant defence, xenobiotic metabolism, hormone clearance, inflammatory regulation, glutathione-related balance, purine metabolism, and environmental exposure responses.
- Rather than measuring current toxin exposure or claiming to determine an individual’s “toxic burden,” this panel provides a personalized genetic framework to help clinicians develop more targeted strategies for nutrition, lifestyle, exposure reduction, supplementation, and laboratory monitoring.
What This Test Covers
Antioxidant Enzyme & Metabolite Activity
Evaluates genetic pathways involved in neutralizing reactive oxygen species and maintaining cellular redox balance, including
- Catalase regulation
- GPX7 regulation
- GSTP1 regulation
- Vitamin C metabolite regulation
Hormone Detoxification & Clearance
Evaluates genetic influences on pathways involved in hormone metabolism, conjugation, regulation, and elimination.
These insights may help clinicians understand genetic tendencies that influence how steroid hormones are processed and cleared.
Inflammatory Modulation of Detoxification
Assesses genetic variation related to IL-6 signalling, a pathway that may interact with inflammatory activity, antioxidant demand, hepatic enzyme regulation, and metabolic balance.
Xenobiotic Metabolism
Evaluates genetic pathways involved in processing compounds encountered from both internal and external sources, including
- Caffeine metabolism
- Reduced Liver Detox Enzyme Activity
Endogenous & Microbial Metabolite Processing
Assesses genetic influences on the processing and clearance of compounds produced through normal human metabolism and gut microbial activity, including
- Bilirubin regulation
- N-acetylglucosaminylasparagine regulation
Purine Metabolism
Evaluates genetic influences on xanthine regulation, a pathway involved in purine breakdown and related metabolic processes.
Environmental Exposure Response
Assesses genetic susceptibility to biological responses associated with environmental exposures, including
- Air pollution sensitivity
- Environmental exposure response
These insights can help guide practical strategies for reducing avoidable exposure and supporting resilience.
Why It Matters
The body’s ability to process and respond to compounds is influenced by a complex interaction between genetics, nutrition, lifestyle, medications, health status, and environmental exposure.
The same exposure or metabolic demand may not affect every individual in the same way.
Who Should Take This Test
This panel is designed for
Functional & integrative medicine practitioners
Physicians and Holistic nutrition professionals
Preventive and longevity-focused clinicians
Practitioners managing complex metabolic and environmental health concerns
What You’ll Receive
Comprehensive Genetic Report
A clean report layout with category, subcategory, and SNP-wise interpretation (based on provider or client preference).
Personalized Insights
Actionable insights for nutrition, lifestyle, supplementation, and additional labs to consider to support long term health.
Provider Portal Access
Secure digital access via the ExtendingME Provider Portal for seamless report viewing and sharing.
SNP-Specific Risk Interpretations
For providers seeking deeper genetic insights, we offer detailed SNP-level interpretations.
- Genetic marker identification (e.g., gene name, rsID)
- Patient genotype results and what it means for your patient's health
- Scientific explanation of how these genes influence specific health traits
Turnaround Time
Results will be available approximately 2 to 3 weeks from the receipt of the sample and will be securely delivered through the Provider Portal, enabling seamless access, viewing, and sharing of reports.
Collection Method
ExtendingME test uses a non-invasive, at-home saliva collection kit, eliminating the need for laboratory visits and enabling seamless integration into clinical workflows.
Meet EMma Soft —
Powering Personalized Medicine
EMma Soft is ExtendingME’s proprietary platform designed to connect every part of your personalized medicine offering—from genetic insights to patient engagement and ongoing care. It brings your entire ecosystem together to support scalable growth and long-term value.
